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An increasing Cq value (47).Nucleic Acids Research, 2016, Vol. 44, No. 13Circulating RNA and microvesicles Circulating RNAs are the preferred target in liquid biopsies, and are therefore highly accessed in molecular diagnostics. The RNA, mainly small RNA, found in cell-free blood plasma/serum is either packaged in microvesicles (e.g. exosomes, apoptotic bodies), associated to lipoproteins such as